| abstract |
Compounds are used for detection and/or imaging of amyloid, plaque, or both of proteins or peptides, for screening or testing the efficacy of inhibitors against amyloidosis and/or fibrillar growth of proteins or peptides, and/or for detection of RNA and nucleolus imaging. The compounds are d8 or d10 metal complexes or salts thereof. The metal complexes of the compounds can bind to amyloid, plaque, or both, of the proteins or peptides and/or RNA, nucleolus, or both. The binding induces accumulation and supramolecular self-assembly of the metal complexes, thereby causing hanges in the photophysical properties of the metal complexes. |