| abstract |
A grading model and a device for detecting benign and malignant degrees of thyroid tumors, and application thereof. The model grades changes of imprinted genes in tumors by calculating the imprinted gene loss expression amount, the abnormal expression amount of imprinted gene copies, and the total expression amount of the imprinted genes, and displays the performance of loss of imprints in tissue and cell samples from patients having thyroid tumors. By means of a method for in situ labeling of imprinted genes, the changes in imprinted genes can be detected objectively, visually, early and accurately, and a quantitative model can be provided, thereby contributing to the diagnosis of thyroid tumors. |