| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_db9efde660b78f98b102046e09d07ab7 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D493-22
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F15-0093
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-06 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D493-22
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F15-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-06 |
| filingDate |
2018-08-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0bccfea2419f7fd2a395483020558206
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a5e3c4149422f5b8b63a40a966925c3d |
| publicationDate |
2020-01-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2020019376-A1 |
| titleOfInvention |
Tdo small molecule inhibitor derivative and antitumor conjugate thereof, and preparation method |
| abstract |
A TDO small molecule inhibitor and an antitumor conjugate thereof, and a preparation method. The inhibitor is 3-(2-pyridin-3-yl-vinyl)-1H-indole and a derivative, and is conjugated with a chemotherapeutic drug cisplatin or irinotecan to form an antitumor conjugate. The advantages of chemotherapy and immunotherapy are combined, and a drug that has high efficiency and low toxicity and achieves the therapeutic effect of improving immunity is obtained. |
| priorityDate |
2018-07-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |