abstract |
An assay system and method for generating quantitative data for a subject by determining an expression level of a biomarker panel in a sample obtained from the subject, the biomarker panel having at least one biomarker selected from a first biomarker group including the genes CDC45, CENPI, CLSPN, ERCC6L, EXOl, NCAPG, and optionally at least one additional biomarker selected from a second biomarker group including the genes BUB1B, CDK1, E2F7, GSG2, NUSAP1, RAD51, and RRM2 in any combination, wherein the expression level is obtained by measuring expression of the biomarker panel in the sample, and wherein the subject has a cancer, or is suspected of having a cancer. The cancer may be, for example, prostate cancer, brain cancer, lung cancer, breast cancer, bladder cancer, or ovarian cancer. |