| abstract |
The present invention relates to: a hybrid bio-ink which comprises a mixture of a first bio-ink obtained by liquefying extracellular matrices of decellularized tissues and a second bio-ink containing alginate or fibrinogen, provides advantages in terms of the survival, proliferation, and differentiation of cells due to excellent biocompatibility, and due to excellent physical strength, does not undergo deformation due to cells even after ionic crosslinking; a method of preparing the hybrid bio-ink; and a method of preparing artificial tissues using same, the present invention comprising: a first bio-ink obtained by liquefying the extracellular matrices of the decellularized tissues; and a second bio-ink containing alginate or fibrinogen, wherein the first bio-ink and the second bio-ink are mixed preferably in a volume ratio (v/v) of 1.5-9:1. |