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filingDate 2019-06-21-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c352b88f51912b8ef1c79fce628ce512
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publicationDate 2019-12-26-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber WO-2019243592-A1
titleOfInvention Preparation, composition and application of a bioactive fluoride-doped calcium phosphate able to induce controlled deposition of fluorapatite
abstract Composition and method of production to obtain a bioactive calcium phosphates doped with fluoride and hydroxyl compounds able to transform, via a slow-controlled precipitation process, into fluorapatite.The composition comprises a) a first component including at least one of the following: calcium-deficient phosphate-tricalciumphosphate, tricalcium phosphate, tetracalcium phosphate, oxyapatite, hydroxyapatite b) a second component including at least one of the following: monocalcium phosphate monohydrate or any other calcium acid phosphate such as calcium dihydrogen phosphate or also meta-phosphoric acid and/or ortho-phosphoric acid, c) two fluoride-releasing molecules and d) a pH regulator. The process comprises a mixing stage, a hydration stage, a dehydration stage and a milling stage in order to obtain de bioactive powder, and a stage of rehydration and bioactive transformation to obtain the final product comprising fluorapatite.
priorityDate 2018-06-22-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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