| abstract |
A novel in vitro system and method for predicting the in vivo behavior, such as absorption time or mechanical strength retention, of biodegradable polymeric implants and medical devices. Data from this in vitro method are correlated to in vivo absorption data, allowing for the prediction of accurate in vivo behaviors, such as absorption times. The system uses a novel bypass loop to maintain the integrity of pH measuring devices to improve the reproducibility of data collected during in vitro testing. |