http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2019237395-A1
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_cdc65598b1597887a5b7b42b226ac184 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-113 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-85 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-113 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-85 |
filingDate | 2018-06-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8ecf59189d87ad2e75155d9a94f4f389 |
publicationDate | 2019-12-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | WO-2019237395-A1 |
titleOfInvention | Method for targeted knockout of human cd357 gene by applying crispr/cas9 system |
abstract | Provided is a method for the targeted knockout of a human CD357 gene by applying a CRISPR/Cas9 system. The method comprises: designing a gRNA according to the PAM design principle of gRNA by means of analyzing the specifics of a human CD357 gene sequence, linking the gRNA with a px459 vector to obtain a recombinant vector for the targeted knockout of the human CD357 gene, and using the gRNA in Jurkat cells to guide a CRISPR/Cas9 system to knock out the human CD357 gene. |
priorityDate | 2018-06-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 25.