| abstract |
A method for synthesizing sucrose-6-ester. The method comprises: (a) in the presence of a polar aprotic solvent, contacting an organic phosphine compound represented by formula I with sucrose and an organic tin compound; (b) removing water to obtain a reaction liquid containing a tin-sucrose adduct; and (c) contacting the reaction liquid containing the tin-sucrose adduct with an acid anhydride compound to prepare sucrose-6-ester. (Formula I). R1, R2, and R3 in formula I each are linear or branched alkyl containing 1-20 carbon atoms, cycloalkyl containing 3-10 carbon atoms, or aryl containing 6-10 carbon atoms; moreover, the R1, R2, and R3 are identical groups, partially identical groups, or different groups. According to the method, the reaction conversion efficiency and selectivity are greatly improved, and the molar yield of sucrose-6-ester can reach more than 92% and even can reach 95.3%; moreover, it is easy to implement industrial application. |