| abstract |
The present invention relates to a novel brominated furanone derivative, a method for preparing same and a pharmaceutical composition containing same as an active ingredient. A novel brominated furanone derivative or pharmaceutically acceptable salts thereof according to the present invention exhibit quorum sensing inhibitory activity of bacteria and allow effective inhibition of the formation of a biofilm of bacteria and inhibition of bacterial growth, and thus are used as a pharmaceutical composition, a functional health food composition, an antibiotic composition, a toothpaste composition or a mouthwash composition containing same as an active ingredient, and thus can exhibit useful effects on oral diseases or inflammatory diseases, e.g. periodontal diseases and the like such as gingivitis and periodontitis. |