| abstract |
The present disclosure addresses the problem of providing a production method for a novel fluoromethyl derivative. The problem is solved by a production method that is for a fluorinated organic compound represented by formula (1) [in the formula, R1 represents an organic group, R2 represents hydrogen, halo, or an organic group, R3 represents hydrogen, halo, or an organic group, L represents a single bond, alkanediyl, -CO-, -CONR-, -NRCO-, -O-CO-, or -CO-O- (in these formulas, each occurrence of R independently represents hydrogen or an organic group), R4 represents hydrogen, halo, hydroxy, or an organic group, R3 and R4 may be linked together, and RX represents hydrogen or fluoro. Note that in the case where R4 is hydrogen, L is -CO-, -CONR-, -NRCO-, -O-CO-, or -CO-O-], the method comprising step A for fluorinating an alkene compound represented by formula (2) [in the formula, a single bond denoted by a wiggly line indicates that a steric configuration for a double bond to which the single bond is bonded is E configuration, Z configuration, or a mixture thereof at an arbitrarily defined ratio. The other symbols are as defined above] by reacting the alkene compound with a fluorine source [the fluorine source is a fluorine source (3a) represented by formula MFn (in the formula, M represents H, a group 1 metal in the periodic table, or a group 2 metal in the periodic table, and n represents 1 or 2)] in the presence of a hypervalent iodine aromatic ring compound (1a), or in the presence of an iodine aromatic ring compound (1b) and an oxidizing agent (A). |