| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f527c324c8628d8df3ed2a927795047e |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-622
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-70596
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-24
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-92 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-66
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6872
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-2803
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-005 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-28 |
| filingDate |
2019-03-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3452508433d77d9c5bbfa014eadfaf46
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f423b37815d2042d3462d4968d5079e4 |
| publicationDate |
2019-11-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2019214332-A1 |
| titleOfInvention |
Cd19-targeted human antibody and preparation and use thereof |
| abstract |
Disclosed are a method for screening a CD19-targeted human antibody by means of phage display technology and the CD19-targeted human antibody, wherein a combined single chain antibody of SEQ1-SEQ5, SEQ1-SEQ6, SEQ2-SEQ7, SEQ3-SEQ8 and SEQ4-SEQ9 can specifically bind to the CD19 protein. The CD19-targeted human antibody can be used for the chimeric antigen receptor technology, for construction as a monoclonal antibody to kill tumor cells through an ADCC or CDC action mechanism, or for combining with other antibodies to construct a bispecific antibody. |
| priorityDate |
2018-05-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |