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filingDate 2019-04-26-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_94bfae112cfa22467bbe535a83cac5f3
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publicationDate 2019-11-07-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber WO-2019212911-A1
titleOfInvention System for detecting micro-neuromas and methods of use thereof
abstract The invention provides methods of diagnosing neuropathic corneal pain by the detection of neuromas, such as micro-neuromas, on the cornea. The invention also features systems for detecting the presence of anatomical features located on an ocular tissue surface that may be a marker for neuropathic corneal pain. The systems feature an in vivo confocal microscope and a computer programmed with a neural network to automate the analysis of the microscope images. The invention provides methods of using the system to identify a micro-neuroma in images collected of an ocular surface and methods of diagnosing neuropathic corneal pain and monitoring treatment of neuropathic corneal pain using a system of the invention. The invention further provides a non-transitory computer readable medium having instructions stored thereon, wherein the instructions, when executed by a processor, perform a method for automatically determining the presence of at least one neuroma on a plurality of images of an ocular surface of a patient.
priorityDate 2018-04-30-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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