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filingDate 2018-04-30-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 2019-11-07-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber WO-2019210377-A1
titleOfInvention Bioactive peptides having high binding affinity to human muscular nicotinic acetylcholine receptor
abstract Two synthetic tetrapeptides having a high binding affinity to human muscular nicotinic acetylcholine receptor (HmnAChR) are provided. A composition for inhibiting contraction of muscle cells is also provided. The composition comprises an effective amount of one of these two peptides. Also provided is a method for inhibiting contraction of muscle cells, which method comprises treating muscle cells with an effective amount of the composition. Further provided is a method for inducing proliferation of epidermal cells, which method comprises treating the epidermal cells with an effective amount of the composition. The epidermal cells may be human epidermal keratinocytes (HEKs).
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