| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_bef032eaf6839e73111a65a0942eb9f2
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f2f481d80549d5201da318938fc439ec
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_41dc944eb862e236c0aad17f9f1df8cf |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-321
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-322
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-115
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-7115
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-712
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0048
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P27-02 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P27-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7115
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-712
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-115 |
| filingDate |
2019-04-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_42cf30b6fa4a113aaddb6a8ec8dde521
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_835127dfa03dfea4af595d74578789ee
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d7433f17b0ba42637ace223304859792
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_73b84c1dd6f69507490e0f5c502874f2
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5a4b52d318b1a1ac85cbf0f325a0ce77
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_df5b79e05d51ceee2ed6e4b7d3acecdc |
| publicationDate |
2019-10-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2019210097-A1 |
| titleOfInvention |
Aptamers with stability, potency or half-life for enhanced safety and efficacy |
| abstract |
This disclosure provides approaches and compositions for improving ocular therapeutics for pediatric and other applications. In general, the compositions and methods are designed to improve vitreous retention of ocular drugs, while simultaneously minimizing serum stability and associated systemic adverse events and retaining therapeutic efficacy. Also provided are aptamers with half-lives and potencies designed to maximize therapeutic efficacy and duration, while minimizing systemic side effects. |
| priorityDate |
2018-04-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |