| abstract |
A delivery device (10, 40, 100) for delivering a substance, such as an insulin formulation, to a patient includes a storage container (12, 112) containing the insulin formulation, a delivery member (20, 42) connected to the storage container by a fluid pathway for injecting the insulin formulation into the patient for delivering the insulin formulation to the patient at a controlled basal flow rate or bolus flow. The delivery device can have a pump mechanism for delivering the substance to the patient. An activated charcoal adsorbent (51, 57, 87) or activated carbon is positioned in the fluid pathway between the storage container and the delivery member for removing at least a portion of a phenolic stabilizing agent from the insulin formulation before delivering to the patient. A method of delivering an insulin formulation to a patient includes the step of contacting the insulin formulation with an activated charcoal or activated carbon adsorbent to remove at least a portion of a phenolic stabilizing agent from the insulin formulation before introducing the treated insulin formulation to the patient. |