| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2efbe95965e682e179dfd266c9980505 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C51-412
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C51-41
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C51-377
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C51-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C215-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C51-373
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C51-353
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J21-18 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C227-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C227-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C213-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J23-6527
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J23-462
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J21-18 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C45-66
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C49-24
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C221-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C225-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01J23-46
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01J23-30
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C49-12 |
| filingDate |
2019-04-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_730180d1aca66cd0349db1d46281ae20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c02261fb3ec99913044f42de5526b779
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d84bc76ec3498f14f84348721dc97bc9 |
| publicationDate |
2019-10-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2019199518-A1 |
| titleOfInvention |
Dehydration and amination of alpha-, beta-dihydroxy carbonyl compounds to alpha-amino acids |
| abstract |
Processes are disclosed for synthesizing an α-amino acid or α-amino acid derivative, from a starting compound having a carbonyl functional group (C=O), with hydroxy-substituted carbon atoms at alpha (α) and beta (β) positions, relative to the carbonyl functional group. An α-, β-dihydroxy carboxylic acid or carboxylate is dehydrated to form a dicarbonyl intermediate by transformation of the α-hydroxy group to a second carbonyl group (adjacent a carbonyl group of the starting compound) and removal of the β-hydroxy group. This dicarbonyl intermediate is optionally cracked to form a second dicarbonyl intermediate having fewer carbon atoms but preserving the first and second carbonyl groups. Either or both of the dicarbonyl intermediate and the cracked dicarbonyl intermediate are then reductively aminated. |
| priorityDate |
2018-04-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |