http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2019196128-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c3e9ac1a8a54862039d2b7dbb9f323b0 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-145 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-125 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0647 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-0789 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-0797 |
| filingDate | 2018-04-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_baf8f730fd5c2eb740766fdb686de6e9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4437e8eeb02240eb74cf4e0fd55c2c02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_016b237eb30698a86efa6bb1f47a5f93 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b94392e80d515eb81c4de8842796b34a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dc3045928e44466193200c93b328e5a5 |
| publicationDate | 2019-10-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | WO-2019196128-A1 |
| titleOfInvention | Culture system and method for expanding hematopoietic stem cell and use thereof |
| abstract | Disclosed are a culture system and method for expanding hematopoietic stem cells and the use thereof. The culture system comprises a cell culture medium containing sodium butyrate. The method comprises obtaining hematopoietic stem cells in a fresh blood sample to use as sample cells and using the cell culture medium containing sodium butyrate for in vitro expansion culture to obtain hematopoietic stem cells. The beneficial effects: 1. Total number of the cells obtained by in vitro expansion of umbilical cord blood hematopoietic stem cells is increased by adding sodium butyrate, providing a preliminary technical foundation for clinical trials; 2. The hematopoietic stem cells following expansion comprise a higher proportion of CD34 + CD90 + cell populations, and possess a even better CFU colony forming ability, suggesting that the hematopoietic stem cells are more primitive and have a stronger differentiation potential to rebuild the blood system and can effectively support clinical treatment needs; 3. In vitro expansion of the hematopoietic stem cells becomes easier, safer and more efficient. |
| priorityDate | 2018-04-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 51.