Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d137f8e7503ba75f6edf7cbdf54e98c7 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B2200-13 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D471-04 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-04 |
filingDate |
2019-02-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9df33f94d36467c7633226973eca5ccc http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9f3cf146c891e09cdcefde981334a269 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c2ca314e21a14446e08d54ca06557268 |
publicationDate |
2019-10-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-2019193428-A1 |
titleOfInvention |
Isothermal reactive crystallisation process for the preparation of a crystalline form of pimodivir hydrochloride hemihydrate |
abstract |
The present invention relates to an isothermal reactive crystallisation procedure to obtain the HCl salt of (2S,3S)-3-{[5-fluoro-2-(5-fluoro-1H-pyrrolo[2,3-b]pyridin-3-yl)pyrimidin-4-yl]amino}- bicyclo[2.2.2] octane-2-carboxylic acid hemihydrate in crystalline form using a solvent system comprising a mixture of water and one or more organic solvents. |
priorityDate |
2018-04-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |