http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2019183620-A1

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filingDate 2019-03-25-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 2019-09-26-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber WO-2019183620-A1
titleOfInvention Non-invasive classification of benign and malignant melanocytic lesions using microrna profiling
abstract Differentiating benign cutaneous lesions from melanoma is an imprecise and subjective endeavor. The use of micro-RNAs has been investigated, but results have not been consistent across studies and clinical applications are lacking. The invention provides new micro-RNA signatures for differentiating benign lesions from melanoma. The micro-RNA signatures are robust, being stable across detection platforms, diverse sample types, and patient populations. The diagnostic methods based on these signatures control for variations in lesion composition and sample diversity, and permit cross-platform comparisons. The micro-RNA signatures and methods are amenable to the use of samples from convenient non-invasive tape strip biopsy.
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