abstract |
The present invention relates to a novel genetically modified NK cell line and a use thereof and, more specifically, provides: a genetically modified NK cell line into which polynucleotides encoding CD7, CD28, cell membrane-bound IL-15 and a TGFβ receptor, respectively, and an apoptotic gene are transduced into an isolated NK cell line; and a use thereof, such as in a pharmaceutical composition for treating cancer, containing the cell line. |