http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2019174995-A1

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filingDate 2019-03-06-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0c38911b587b7aecb6921a89c203c04d
publicationDate 2019-09-19-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber WO-2019174995-A1
titleOfInvention Sublingual tablet comprising sildenafil citrate
abstract The invention is directed to a sublingual tablet comprising sildenafil citrate in an amount comprised between 10 mg and 150 mg, and a non-ionic surfactant in an amount comprised between 20 and 100 % by weight of the amount of sildenafil citrate, wherein the nonionic surfactant is a polyethoxylated compound comprising a polar and a non-polar part, wherein the polar part of the molecule comprises from 3 to 8 ethoxy groups and the non-polar part is a C4- C20 alkyl group or a C7-C20 aryl group. The sublingual tablet is prepared by a process that comprises the following steps: introducing sildenafil citrate into a mixer; adding to the mixer containing sildenafil citrate the nonionic surfactant in at least three aliquots and mixing for 5 minutes after the addition of each aliquot. The tablet according to the invention is characterized by a high concentration of sildenafil, is easy to take, and with a good taste in the mouth.
priorityDate 2018-03-13-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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