| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9da092435bda0b363f6419a4f5bb5fbd
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_015db2aced17a2d6ce7c648ebdabef06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ea434bb281345d5867f8092bb62bd414
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d7b57b5bf363901afffc82c97caf5ac0
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c430c10505149d45686726b082f5e06c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_50eb752940fa4aa36756a6bc9f6f3504
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c9aa36f41d88137d91daa2bceeb26946
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5894d694d4a784d601f503d79e518f2d |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-505
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-76
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-324
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-565
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-21
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-32
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-54
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-545 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-40
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-92 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-50
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-395 |
| filingDate |
2019-03-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a5c41d8d5689ae346e71e6dc82405562
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5f41cd7603ed3a8fdf7f6143ada2ec95
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a17eeae189c08ec6b82f8c39e40fc3e7
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_212ffa00af5662c1707acd7b744480b7
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0f4a2bc1d2c6eb8087626566487a06d8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4540d612b896f3c9c55a527591745772 |
| publicationDate |
2019-09-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2019173530-A1 |
| titleOfInvention |
Use of pcsk9 inhibitor for reducing cardiovascular risk |
| abstract |
The present invention provides methods for treating diseases and disorders that are associated with elevated levels of lipids and lipoproteins. The methods of the present invention comprise administering to a high cardiovascular risk patient a pharmaceutical composition comprising a PCSK9 inhibitor. In certain embodiments, the PCSK9 inhibitor is an anti-PCSK9 antibody such as the exemplary antibody referred to herein as mAb316P or alirocumab. The methods of the present invention are useful for treating high cardiovascular risk patients with hypercholesterolemia and elevated levels of other atherogenic lipoproteins that are not adequately controlled by maximum tolerated dose statin therapy. In particular, the methods of the present invention are useful for reducing cardiovascular risk and lowering atherogenic lipoproteins in high cardiovascular risk patients within 12 months following an acute coronary syndrome event despite a maximum tolerated dose statin therapy. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11673967-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-4063506-A4 |
| priorityDate |
2018-03-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |