http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2019172452-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_cd727aa2b4e6c347aadd94971881d671 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-50 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-50 |
| filingDate | 2019-03-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b4f66ab89f93d1e2c318900a7f681171 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6ac1946c0310ab62ff1436b8c072757f |
| publicationDate | 2019-09-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | WO-2019172452-A1 |
| titleOfInvention | Method for evaluating skin barrier function, and method for visualizing degree of skin barrier function |
| abstract | The present invention provides a method for evaluating skin barrier function, including: (1) a step for adding a membrane-environment-sensitive dye to a three-dimensionally cultured epidermis having a stratum corneum and a stratum granulosum and culturing; (2) a step for irradiating the three-dimensionally cultured epidermis at an excitation wavelength for the membrane-environment-sensitive dye and sequentially detecting the fluorescence intensity of a gel-phase peak wavelength and the fluorescence intensity of a liquid-crystal-phase peak wavelength emitted from the membrane-environment-sensitive dye; (3) a step for calculating fluidity (GP), plotting the fluidity (GP) to create a fluidity distribution, and determining a first maximum value; and (4) a step for determining a skin barrier function value. The present invention also provides a method for visualizing the degree of skin barrier function. |
| priorityDate | 2018-03-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 73.