Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2e3830f35387a1c32061dea3ee310851 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2750-14143 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2750-14121 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2750-14122 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-005 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-86 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-864 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-005 |
filingDate |
2019-02-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fab790ac603cb62013ad51e81938d86a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_783a00cbee1809dc6a8ed32d53834da9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5a60de7ad1651f87ed426bc42e3c06eb http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f0265e872b156982675234b48faf9926 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f551bb993696a5d32ef0dab6fcead0c3 |
publicationDate |
2019-10-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-2019169004-A9 |
titleOfInvention |
Novel adeno-associated virus (aav) vectors, aav vectors having reduced capsid deamidation and uses therefor |
abstract |
A recombinant adeno-associated virus (rAAV) vector comprising an AAV capsid having a heterogeneous population of vp1 proteins, a heterogeneous population of vp2 protein and a heterogeneous population of vp3 proteins. The capsid contains modified amino acids as compared to the encoded VP1 amino acid sequence, the capsid containing highly deamidated asparagine residues at asparagine - glycine pair, and further comprising multiple other, less deamidated asparagine and optionally glutamine residues. |
priorityDate |
2018-02-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |