http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2019168324-A1

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filingDate 2019-02-26-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c7c82927c70a27f40117c35d0dc3cb8f
publicationDate 2019-09-06-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber WO-2019168324-A1
titleOfInvention Composition for preventing and treating hormonal disorder or andropause in males, containing, as active ingredient, combination of compounds comprising flavonoid derivatives and iridoid derivatives, and use thereof
abstract The present invention relates to a composition for preventing and treating hormonal disorders or andropause in males, containing, as an active ingredient, a herbal medicine extract comprising a combination of compounds comprising flavonoid derivatives and iridoid derivatives, and a use thereof. In an experiment for measuring the effects of a combination comprising (a) monotropein, (b) kaempferol 3-glucoside and (c) quercetin 4'-glucoside (spiraeoside) on the weight of the testes by using an in vivo varicocele animal model, the weight of the left testis in a normal group to which a drug had been administered slightly increased over that of a normal group, and the weight of the left testis in a varicocele mouse group to which a drug had been administered significantly increased over that of a varicocele mouse group. In addition, it has been confirmed that a varicocele mouse group to which a drug is administered has blood testosterone and antioxidant activity-related blood SOD and GSH-Px activities that remarkably increased over those of a varicocele mouse group, and thus the present invention can be effectively used in a pharmaceutical composition, a functional health food and a health supplement for the prevention and treatment of hormonal disorders or andropause in males.
priorityDate 2018-02-28-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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Total number of triples: 39.