http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2019167059-A1

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http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61B8-15
filingDate 2019-02-20-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f0b6f73a8fd4439536d675ce586869ed
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publicationDate 2019-09-06-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber WO-2019167059-A1
titleOfInvention Multilayer skin tissue models and methods of preparation thereof
abstract The disclosure provides for an optical phantom mimicking the diffuse reflectance spectral (DRS) response from human tissue such as skin forearm over a wide spectral range from 280-670 nm. The optical phantom includes at least an epidermal layer, dermal layer, a base layer and a hard tissue layer. The hard tissue layer is obtained by coating a mixture of barium sulphate and xanthan gum over a glass surface. The base layer is obtained by coating a bulk solution of gelatin and intralipid on the glass surface. The dermal layer is obtained by coating the bulk solution additionally containing collagen and haemoglobin. The epidermal layer is prepared from NADH (Nicotinamide Adenine Dinucleotide), FAD (Flavin Adenine Dinucleotide) and coffee solution added to the bulk solution. The disclosed phantom finds use in characterizing and validating the performance of fiber based DRS probes for optical biopsy.
priorityDate 2018-02-28-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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