Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_fa08f4179e2ca473c2567f710412424d |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P13-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-167 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P13-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-167 |
filingDate |
2018-03-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a42852f7d766105e556b182efea7185a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ce947c27252b04abdd79d5aa8299167c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_71703ee15e0d3715953b860c80ca2bea http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dadf3919a2a2c0e1ef73745b91232c62 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_71dd699130d5d3f8e0be5bcc111d728f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5feb02ea5b494cd0a0436e3bd943a94f |
publicationDate |
2019-09-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-2019165622-A1 |
titleOfInvention |
Use of niclosamide ethanolamine salt and pharmaceutical composition thereof |
abstract |
Provided is the use of a niclosamide ethanolamine salt and a pharmaceutical composition thereof. The salt and the composition play an uncoupling role for renal mitochondria, reduce proteinuria excretion in mice with kidney diseases, improve glomerulosclerosis and renal tubule lesions, and decrease serum creatinine levels. Therefore, the niclosamide ethanolamine salt and the pharmaceutical composition thereof have a certain protective effect on the kidneys and can be used for preventing and treating kidney diseases. |
priorityDate |
2018-03-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |