http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2019161031-A1

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filingDate 2019-02-14-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6a531ff6f4e748adbb28dc4257462f8b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7f517086d7d145f404327bb320f4e489
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publicationDate 2019-08-22-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber WO-2019161031-A1
titleOfInvention Barcoded molecular standards
abstract High throughput personal genomic testing has created a need for robust quality control mechanisms to track sample identity, reagent integrity, and other factors with significant influence on assay performance. A method of massively parallel sequencing using an accompanying barcoded molecular standard enables one to track nucleic acid analytes to identify them by project, lot, batch, or patient. The molecular standard contains sequences present in the analyte, allowing it to be processed simultaneously without any other additional reagents. Within the molecular standard, a calibrator sequence permits assessment of fidelity of sequence determination. Additional sequences in the molecular standard may be used to manipulate the molecular standard separate from the analyte. The molecular standard can be used to benchmark sequencing platforms and assess error rates.
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priorityDate 2018-02-15-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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