http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2019155576-A1
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f97f0fa258a008bf056ad04b7f380dda |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-54393 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6848 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6854 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-543 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-53 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-549 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68 |
filingDate | 2018-02-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_21b30d1cd9bff9f121abd11191304483 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8d0d3e565f3c6eaf94f672fef83c25ba |
publicationDate | 2019-08-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | WO-2019155576-A1 |
titleOfInvention | Method for improving result of monoclonal antibody detection |
abstract | Provided is a method for detecting a monoclonal antibody in a sample, said method comprising (a) a step for capturing a monoclonal antibody in a sample and immobilizing the monoclonal antibody in a pore of a porous body, (b) a step for contacting the porous body in which the monoclonal antibody is immobilized with a nanoparticle in which a protease is immobilized and thus selectively digesting the monoclonal antibody with the protease, and (c) a step for detecting peptide fragments obtained by the selective digestion with the protease by liquid chromatography/mass spectrometry (LC-MS), wherein the selective digestion with the protease in step (b) is carried out in the presence of a chaotropic reagent and a reducing agent under conditions with pH 8-9. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2022270126-A1 |
priorityDate | 2018-02-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 360.