| abstract |
The present invention relates to a novel multivalent HPV DNA vaccine, a fusion protein used therein, and a polynucleotide for encoding the fusion protein and, more particularly, to a multivalent HPV DNA vaccine composition comprising polynucleotides for encoding early protein antigen 6 (E6) of 6, 11, 16, 18, 39, 45 and 56-type human papillomaviruses (HPVs) or an immunogenic fragment thereof, and early protein antigen 7 (E7) or an immunogenic fragment thereof, respectively. |