Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d71f4d06c9a84c3b0d6f69d842a84175 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a25729437bb759a0e8c52360ecbe5eee http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_68d80933a35bd9437a0da03fd5bfb590 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4913776ffabab8861f9175157fe378a8 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B82Y5-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2320-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-14 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y301-03005 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-465 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-6911 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-1075 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-127 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-1137 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-1138 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-713 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-87 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7105 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-127 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-113 |
filingDate |
2019-01-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0839657d64091d4094d61f41be23e88f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c854612b7d529b3747b1e916bf89789f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b48bb213cf0e662f45081ab3d875c475 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c022acd56edf24246ad9b284f4b1142d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bfe7286b2caff5454d106249a8ac15a1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0175bfecbfe6597ae71e953e5362f550 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_68bab5004cf9ce3939f43a617ffa1591 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_283fbbe98f7d3706b2b9ef82db530ad0 |
publicationDate |
2019-08-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-2019144209-A1 |
titleOfInvention |
Nanometric pharmaceutical composition for release of interfering rna molecules and use thereof |
abstract |
The present invention relates to a nanometric-scale composition in the form of liposomes or nanoemulsions containing strands of interfering RNA (siRNA) capable of silencing the gene responsible for the expression of superexposed adhesion proteins in tumours, such as the enzyme ecto-5'-nucleotidase/CD73 (CD73) which is superexpressed in multiform glioblastoma and in other types of tumour. The binding of the liposomes or nanoemulsions to the siRNA promotes a site-directed release complex capable of being incorporated into various types of formulation, such as an intratumoral or intravenous injection or nasal administration. |
priorityDate |
2018-01-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |