http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2019143806-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_280d87031f0c5786de1808713a1b76b7 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D473-14 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-519 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-00 |
| filingDate | 2019-01-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_37c67978e979a4c392f92a2880c86dc4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_94581ad180aedc244f03aabfcdb738b1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_33c35f433862e2b3f14a84c9f8307d22 |
| publicationDate | 2019-07-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | WO-2019143806-A1 |
| titleOfInvention | Caffeine-embedded triazabutadienes and methods of use |
| abstract | Triazabutadiene compounds comprising caffeine, a caffeine analog such as istradefylline, or the like. The caffeine triazabutadienes may be used for treating diseases or conditions, or ameliorating symptoms of particular diseases or conditions. For example, the caffeine triazabutadienes may be targeted to the A2A receptor in the brain for treating or ameliorating symptoms of Parkinson's disease. Cleavage of the caffeine triazabutadienes of the present invention yields a caffeine derivative, which may function as a caffeine-like drug to inhibit function of the A2A receptor, and a diazonium species, which may react with tyrosine residues of the A2A receptor. The diazonium reaction with the tyrosine residues may block the release of the caffeine derivative and/or block an agonist compound from interacting with the A2A receptor. |
| priorityDate | 2018-01-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 68.