http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2019143777-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_fd43340199b2db617e673de004a52b50 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61M2205-3553 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61M2205-3592 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61M2210-0612 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61M2205-3584 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0048 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61F9-0008 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0048 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-46 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61M11-005 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61F9-0008 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P27-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61M11-001 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-46 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61M11-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61M15-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61B5-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61F9-00 |
| filingDate | 2019-01-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4c04e8f4cb988035c4059df5377037ac http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5827699fca24680ccafab9e303e17493 |
| publicationDate | 2019-07-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | WO-2019143777-A1 |
| titleOfInvention | Methods and devices for delivering atropine to the eye as a micro-dose stream of droplets |
| abstract | The present disclosure provides methods and devices which improve upon prior art methods and devices for delivering atropine to the eye. In certain aspects, the disclosure provides method for delivering a composition comprising atropine to an eye of a subject in need thereof as a micro-dose stream of droplets. The method generally includes, (a) generating a micro-dose stream of droplets including the composition comprising atropine via a piezoelectric droplet delivery device, wherein the micro-dose stream of droplets has an average ejected droplet diameter greater than 15 microns; and (b) delivering the micro-dose stream of droplets to the eye of said subject. In certain embodiments, the method treats myopia, in particular progressive myopia (nearsightedness) in adults and children, in the subject in need thereof. Specifically, the present disclosure utilizes relatively high concentrations of atropine in the solution to be administered, contrary to current trends, but delivers a much smaller dose to a subject, which thereby reduces, and even prevents, excess fluid from being unabsorbed by the target tissues. Maintaining higher concentrations of atropine in the solution to be administered may also reduce or avoid issues with the instability of lower concentration solutions. |
| priorityDate | 2018-01-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 36.