http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2019142717-A1

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filingDate 2019-01-10-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0a6fa9d5a85c95147069c19844ad31f6
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publicationDate 2019-07-25-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber WO-2019142717-A1
titleOfInvention Mutant polyhydroxyalkanoic acid synthase, gene and transformant thereof, and method for producing polyhydroxyalkanoic acid
abstract Provided is a mutant PHA synthase that achieves production of a PHA copolymer having a high or low 3HH ratio while maintaining PHA productivity. Mutant polyhydroxyalkanoic acid synthase having an amino acid sequence that exhibits 85% or more sequence identity with an amino acid sequence shown by SEQ ID NO: 1 and that includes one or more mutations from among (a)-(c) below. Mutation (a): a mutation in which serine 389 from the N-terminal of the amino acid sequence shown by SEQ ID NO: 1 is substituted by an amino acid other than serine; mutation (b): a mutation in which leucine 436 from the N-terminal of the amino acid sequence shown by SEQ ID NO: 1 is substituted by an amino acid other than leucine; mutation (c): a mutation in which 11-19 amino acid residues are deleted from the C-terminal of the amino acid sequence shown by SEQ ID NO: 1.
isCitedBy http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2022113530-A1
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