| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_51872a5a09cc9a30fcbd1153ee34cdc6 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B2200-13 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D263-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D403-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D413-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D413-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C237-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C59-245
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-506
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D239-34 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C237-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D239-34
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D263-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D413-14 |
| filingDate |
2019-01-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ad303c4224e5ede8d2dddca60bc9a25e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3acb13d4ec001bca1e24a470a79ec24b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2868456299e088c8d8ed534855f10db7
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dcd294164e4850d0611167167a39aeb8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f2c7c7499202f8bce5b4e4058707cb31
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c2e49f3fde7d6c721b898a677a8e34d6
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_27d18bb3fcefc0cf0efff32936af18fb
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2f187dd7443ef6a50112269ac32cf6ab
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4bb5c92a19de06a0e50d6b752a263f56 |
| publicationDate |
2019-07-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2019140095-A1 |
| titleOfInvention |
Novel processes and intermediates for the preparation of soluble guanylate cyclase stimulators |
| abstract |
The present disclosure relates to novel processes for the preparation of compounds of Formula I. Some of these compounds are useful as stimulators of soluble guanylate cyclase (sGC). Others are useful intermediates towards the preparation of said stimulators. These processes are amenable to large scale preparation and produce stable 3-(2-pyrimidinyl)pyrazoles of Formula I in high purity and yields. The present invention has the additional advantage of facile reaction conditions, amenable to scale up for large scale manufacturing. The disclosure also provides novel intermediates useful in the preparation of said compounds. |
| priorityDate |
2018-01-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |