| abstract |
The present invention relates to production of an oxygen-releasing hydrogel for bioinjection. A new type of oxygen-releasing in situ cross-linked hydrogel thus produced is formed as a hydrogel by inducing, by means of calcium ions released by decomposition of calcium peroxide, ion coupling with a negatively charged polymer, and generates and releases highly concentrated oxygen inside the hydrogel. Additionally, the present invention is novel in originating from the first of the studies into formation of a hydrogel using existing alginates to produce a hydrogel using calcium peroxide, is able to improve the limitations of existing oxygen-delivery systems, allows the production of oxygen-releasing hydrogel for bioinjection by a simple and rapid method without chemical synthesis, and has the further advantage of allowing the physical, chemical and biochemical characteristics of the hydrogel to be easily controlled in accordance with production conditions. |