http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2019116296-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4e93a1fb96cc1d016754bb322920bd62 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01L2300-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01L2300-0877 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01L2400-049 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01L2400-0633 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01L2300-0829 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01L2200-143 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01L3-502715 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01L3-50273 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01L3-0293 |
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N15-10 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01L3-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N35-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01L3-02 |
| filingDate | 2018-12-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5d960aec2a33e23caf883c895694353a |
| publicationDate | 2019-06-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | WO-2019116296-A1 |
| titleOfInvention | Methods and assemblies for high throughput screening |
| abstract | According to the present invention there is provided various methods for screening a plurality of sample fluids for molecules which can bind to predefined ligands, using the assembly comprising, a sample delivery unit which can receive sample fluids to be screened, and a plurality of groups of flow cells, each group having at least two flow cells, and a means for selectively fluidly connecting the sample delivery unit to any one of saidgroups of flow cells, the method comprising the steps of, selecting one of said plurality of flow cell groups by fluidly connecting said flow cell group to the need unit; carrying out an injection step which comprises injecting a sample fluid to be screened from the sample delivery unit into the flow cells in the selected flow cell group; for each flow cell in the flow cell group, recording a signal using a sensor which represent the binding of molecules of the sample fluid to ligands on the test surface of that flow cell and/or the dissociation of molecules from ligands on the test surface of that flow cell; carrying out a damage assessment step, using said recorded signals, to determine if the test surface of a flow cell in the selected flow cell group is damaged; if it is determined from the damage assessment step that the test surface of a flow cell in the selected flow cell group is damaged, then selecting another one of said plurality of flow cell groups by fluidly connecting said other flow cell group to the need unit; injecting the next sample fluid to be screened from the sample delivery unit into the flow cells in said other flow cell unit. There is further provided assemblies which can be used to implement the afore-mentioned methods. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-7244559-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/DE-102020107645-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113495057-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2021165733-A |
| priorityDate | 2017-12-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 31.