| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ef2dcf1445c02e75f548c4c51be3b34c |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-85
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-28 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P21-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-47
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-63 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-85
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-28
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-19
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-21 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-63
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-12 |
| filingDate |
2018-11-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5da8bc81e44c0588af05f1e372d50171
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e5835499e76988eabee5b192a6cbc160
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3d52a299a542de6e167d1e0d631a700d |
| publicationDate |
2019-06-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2019114534-A1 |
| titleOfInvention |
Fermentation production process for protein drugs |
| abstract |
The present invention discloses a fermentation production process for protein drugs, which is suitable for industrial fermentation production of sDSS1 protein drugs. The process comprises steps of: firstly employing a genetic engineering means to integrate an sDSS1 gene fragment into an expression plasmid, the integrated gene fragment comprising a purification tag; transforming and introducing the expression plasmid into a corresponding expression host, so as to construct recombinant engineering cells with a high level of expression; fermenting, expressing by induction, lysing, renaturing, and enzyme-digesting the recombinant engineering cells to obtain a crude pure protein; and continuing to conduct a series of fine purification steps to obtain a high-purity sDSS1 protein. The process is economical and effective. |
| priorityDate |
2017-12-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |