| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_087bed7abab91ae0f927879f9fe8b273 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J2231-546
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J2531-821
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J2231-543
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J2531-0288 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J31-2278
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J31-2273
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J31-226
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D313-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J31-2208 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D313-00 |
| filingDate |
2018-12-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f0f995bdd7e0e76c8758a847032f4a36
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ede823624b86e92f1c6458da6821abd5
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7aadc2b7da9008217237055538d4b549 |
| publicationDate |
2019-06-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2019113019-A2 |
| titleOfInvention |
Using stereoretention for the synthesis of e-macrocycles with ruthenium-based olefin metathesis catalysts |
| abstract |
This invention relates generally to the synthesis of E -macrocycles using stereoretentive ruthenium olefin metathesis catalysts supported by dithioiate ligands. Macrocycles were generated with excellent selectivity (>99% E) and in moderate to high/good yields (47% to 80% yield; 58% to 80% yield) from diene starting materials bearing two E -olefins or bearing one E - olefin and one terminal olefin, A variety of rings were constructed, ranging from 12- to 18- membered macrocycles, including the antibiotic recifeiolide. The invention has utility in the fields of organometallics and organic synthesis. |
| priorityDate |
2017-12-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |