| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f8c0982b0f02b1ed6d20a315370a3a3a |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-976 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y304-21004
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-68
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-37
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-6427 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H19-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H17-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H19-04 |
| filingDate |
2017-12-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d63219cce1d5cfe6a24904c5c9f54183
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a5412f3a1b9400b9e6bd23619307c827
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8f95772f1578b0d8f2b0791d2355ec13 |
| publicationDate |
2019-06-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2019112567-A1 |
| titleOfInvention |
Methods and compositions related to selecting variant proteases |
| abstract |
This invention provides protease activity screening matrices that contain a solid support conjugated to a substrate moiety that can be specifically cleaved by a specific protease. The invention also provides methods for utilizing the protease activity screening matrices described herein For identifying a variant protease that recognizes a desired substrate cleavage site. The invention additionally provides specific variant trypsin enzymes or enzymatic fragments that have citrulline-dependent proteolytic activities. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11351543-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11351544-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11247209-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11123735-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110426514-A |
| priorityDate |
2017-12-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |