abstract |
The present invention relates to the field of pharmaceutical chemistry. In particular, the present invention relates to a PARP/PI3K double-target inhibitor (I) containing structures of 5,6,7,8-tetrahydropyrido[3,4-d]pyrimidine and phthalazin-1(2H)-one and a preparation method thereof. The compound has PARP/PI3K double-target inhibitory activity as proved by pharmacodynamic tests and can be used against a tumor. |