Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c176fa5c1c9df39884f57332bd9238c0 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02A50-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2740-15041 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-572 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-555 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-12 |
filingDate |
2018-11-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b654677c031ac20212ee94f4703d36e7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2b200724f0ee8339105076d91955b9f2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_85c9148b4ee088d9bf938b52298e6f12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4616b6d916e48bc1d0ae8a9a6de2e765 |
publicationDate |
2019-06-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-2019106432-A2 |
titleOfInvention |
Viral vector constructs for expression of genetic adjuvants mimicking cd40 signaling |
abstract |
Viral vectors are provided for use as genetic immunotherapeutic agents, including preventive and therapeutic vaccines as well as compositions to enhance cellular immune responses. The vectors are particularly useful for treating or preventing cancer and infectious diseases. The vectors include lentiviral vectors that encode one or more antigens and an adjuvant, and optionally may encode one or more soluble checkpoint inhibitor molecules. The adjuvant is full-length latent membrane protein 1 (LMP1) from Epstein Barr virus which has been codon optimized for human expression. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112458058-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112458058-B |
priorityDate |
2017-11-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |