| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_cb351a5a4e03ee3773bd0df5dbae9ac3 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y403-01
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-1031
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-70
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-88 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-88
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-70
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-21
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-10 |
| filingDate |
2017-12-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_de2ca0225c9445cb07131cc2a76bd00a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9b0f078d6ea25962953e9854f35afe51
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fd6612316303a1c8b6adebfe93271f9e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_85b383a68e3b72e8b4fe49671460dab7
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5a782018a51edbf5c2505fc6b1b962ad |
| publicationDate |
2019-06-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2019104759-A1 |
| titleOfInvention |
L-amino acid deaminase mutants having increased thermal stability and construction method therefor |
| abstract |
The present invention relates to the field of biotechnology, and provides L-amino acid deaminase mutants D340N and L363N having increased thermal stability and a construction method therefor. Compared with wild-type L-amino acid deaminase, Vmax and t1/2 of the mutants D340N and L363N are increased. The mutants can be used for catalyzing L-amino acid deamination to synthesize corresponding α-keto acid, and can be used as a catalyst for chirally-separated amino acids and derivatives thereof so as to realize separation of D\L-amino acid enantiomers. |
| priorityDate |
2017-11-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |