http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2019103373-A3
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5448803c9d55cede465d50890fdfe559 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-58 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-143 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-146 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-58 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-14 |
| filingDate | 2018-11-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_26adec8a8fc21266f58ecb19fb5efd80 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_74b20b2531dc0b7c904a222adc3db14c |
| publicationDate | 2019-07-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | WO-2019103373-A3 |
| titleOfInvention | Solid dispersion of dutasteride, method for producing same, and pharmaceutical composition comprising same |
| abstract | The present invention relates to a solid dispersion of dutasteride for improving the solubility or dissolution of dutasteride which is a poorly soluble drug, a method for producing the same, and a pharmaceutical composition comprising the same. More specifically, the solid dispersion of dutasteride comprises: a co-precipitate including dutasteride and a water-soluble polymeric carrier; and an adsorbent, wherein the co-precipitate contains of the dutasteride to the water-soluble polymer carrier in the ratio of 1:10-100 % by weight. The present invention exhibits a dissolution rate equal to or higher than that of an Avodart® soft capsule, and at the same time, exhibits excellent storage stability by further minimizing the generation of a flexible substance as compared to the same. |
| priorityDate | 2017-11-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 24.