http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2019102602-A1
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_80541a317b1ced25ceb4e70c58aa2c67 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c8f83b3ff5eb9afeda19d0dddb490138 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K36-185 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K36-752 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-15 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K36-752 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-15 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K36-185 |
filingDate | 2017-11-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7b9450c23fe6a05c14b711705dfc47c9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4af626283959a28f5b10536a50ea851e |
publicationDate | 2019-05-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | WO-2019102602-A1 |
titleOfInvention | Screening method |
abstract | Provided is a screening method with which it is possible to determine whether a subject composition promotes CRE-related CREB-dependent long term memory gene transcriptional activity or CRE-dependent long term memory gene transcriptional activity. This screening method, whereby a composition is screened to determine whether the composition promotes CRE-related CREB-dependent long term memory gene transcriptional activity or CRE-dependent long term memory gene transcriptional activity, comprises: a step for measuring long term memory learning transcriptional factor activity, wherein the CRE-related CREB-dependent long term memory gene transcriptional activity or CRE-dependent long term memory gene transcriptional activity of the composition is measured in the presence of an inhibitor selected from the group consisting of PD98059, U0126, GF109203X and H89; and a step for determining CREB-dependent long term memory learning transcriptional factor activity, wherein the CRE-related CREB-dependent long term memory gene transcriptional activity or CRE-dependent long term memory gene transcriptional activity of the composition obtained in the step for measuring long term memory learning transcriptional factor activity is compared with the CRE-related CREB-dependent long term memory gene transcriptional activity or CRE-dependent long term memory gene transcriptional activity of nobiletin at a prescribed concentration so as to determine whether the activity of the composition is higher than the activity of nobiletin. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2023127291-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-7320593-B2 |
priorityDate | 2017-11-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 56.