| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1b87734b9fb6807a966e2c79cf967856
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2c27f4a786895417d03d0b1045587100 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-55522
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2710-24043
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2710-24034
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-55533
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-5154
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2710-10343
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-55505
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2710-10234
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-32
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-53
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-575 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-86
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-4747
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-555
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-85
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-4727
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-39
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-0011
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-70521 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-555
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-85
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-863
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-861
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K19-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-235
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-39
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-275
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-00 |
| filingDate |
2018-11-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_46cdfd19276fe0b1ce2da9ddddb7dac1
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0e6816c06ee203cc726af0b5719e17eb
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a539a7adbfd2b4eb69234d5da8d6223a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_138f1d2245f6656e5c8b7ee09c6df760
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0cbc141545842adb3eb6abe4d8331b39
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0418fe1e24a118c22b35139b6e733cf4
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9847286c385e7c0d3628c9830e75473a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_579e4f2bac24d752058417c74400354d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3b11c08a692bc34ce1bcc9c50547fe65 |
| publicationDate |
2019-06-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2019101062-A9 |
| titleOfInvention |
Recombinant vaccine and application thereof |
| abstract |
The present invention relates to the technical field of biotech drugs and in particular relates to a recombinant vaccine and an application thereof. The present invention provides a molecular assembly, comprising soluble PD-1、MUC1 and Survivin. A vaccine prepared by the molecular assembly can produce good immunogenicity and anti-tumor activity. The vaccine immunity provided according to the present invention can produce specific antibody responses and specific cellular immune responses for MUC1 and Survivin. Compared with DNA vaccine CpDV-IL2-MS, CpDV-IL2-sPD1/MS has a more significant anti-tumor effect in tumor-bearing mice. The invention further provides a combination of therapeutic vaccines and chemotherapeutic drugs. |
| priorityDate |
2017-11-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |