abstract |
The present invention relates to the field of pharmaceutical chemistry, and specifically relates to a class of poly (ADP-ribose) polymerase 1 (PARP-1) and phosphatidylinositol-3-kinase (PI3K) dual target inhibitors (I) comprising a benzofuran structure, a method for preparing the same, and a pharmaceutical composition comprising such compounds. Pharmacodynamic tests have demonstrated that the compounds of the present invention have anti-tumor efficacy. (I) |