http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2019096095-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d62d92aaf868f7c4e0a1c6445ca2a3c1 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4745 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4745 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-64 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-60 |
| filingDate | 2018-11-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_10f8d7abc332d415f0b58b06487f2bcc http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b67171b6bdb395ea74a1287761bce66a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8f2ff223b97dba1e3a8c85e5f28bf585 |
| publicationDate | 2019-05-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | WO-2019096095-A1 |
| titleOfInvention | Integrin receptor-targeted anti-cancer conjugate |
| abstract | Disclosed is a heptane sulfonate of a targeted drug conjugate modified by a multi-arm, water-soluble polymer. The typical heptane sulfonate of the conjugate comprises one to eight molecules of heptane sulfonate. Preferably, each branch respectively binds to a conjugate with two molecules of heptane sulfonate, and the preferred heptane sulfonate of the conjugate is eight molecules of heptane sulfonate. The present invention is a targeted anti-cancer conjugate modified by the multi-arm polymer, wherein modification by the water-soluble polymer can enhance the water solubility of the conjugate and increase a drug loading amount; and a targeting molecule enhances the targeting property, allowing the conjugate to be at a higher concentration in a target tissue. |
| priorityDate | 2017-11-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 69.