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filingDate 2018-11-14-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 2019-05-23-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber WO-2019095056-A1
titleOfInvention Dantrolene and analogs thereof for the chronic treatment and prevention of dyssynchronous cardiac dysfunction
abstract The present disclosure relates to methods for the chronic treatment of dyssynchronous cardiac dysfunction (including non-arrhythmia cardiac dysfunction such as heart failure, cardiomyopathy, viral myocarditis, ischemia induced cardiomyopathy, ischemia, chemotheraphy, pacing induced cardiomyopathy or ion channel mutation related dysfunction) and for the prevention or treatment of diseases or conditions associated with dyssynchronous cardiac dysfunction. The method comprises chronically administering to a patient an effective amount of dantrolene, or derivative or analogs thereof (such as azumolene).
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